Use Zolmist Nasal Spray exactly as your doctor tells you to, and you must follow his or her instructions. Keep the repellent on you at all times, because attacks can happen at any time. Even if you feel better, don’t skip any doses and finish the whole course of therapy. If you forgot to take a dose, take it as soon as you remember.
Some of the bad effects of this drug are dry mouth, nausea, changes in taste, drowsiness, and peripheral neuropathy (tingling and numbness of feet and hands). Do not drive or use heavy equipment until you know how this medicine makes you feel. Tell your doctor if you have heart disease, because some types of heart disease make it dangerous to take this medicine.
What are the parts of Zolmist?
Zolmist’s active ingredient is zolmitriptan 5mg/ml in an aqueous solution. This is a serotonin agonist that can treat migraines. Each bottle of Zolmist nasal spray has 7 doses of 5mg/0.1ml. Each dose is dispensed by a spray pump that measures out the right amount.
Zolmist is used to treat migraines.
Zolmist Nasal Spray 5mg has zolmitriptan in it, which can treat migraine attacks with or without aura. Aura is the feeling of seeing or smelling things that aren’t normal and it’s often the first sign that a migraine headache is coming on. Zolmist nasal spray contains zolmitriptan which is a serotonin agonist. It acts like serotonin (also called 5-hydroxytryptamine, or 5-HT) by binding to serotonin receptors in the blood vessels of the brain.
Migraines are painful, throbbing headaches that usually only affect one side of the head. It is due to one of the many migraine triggers that cause blood vessels in the brain to widen or expand. This makes nearby trigeminal sensory neurons send out neuropeptides, which are chemicals in the brain that cause pain and inflammation. Zolmitriptan in Zolmist nasal spray turns on serotonin receptors in these dilated blood vessels, which causes them to close (vasoconstriction). It also slows down the activity of the trigeminal nerve, which relieves pain. The anti-migraine effect of zolmitriptan in Zolmist nasal spray, which relieves headaches and other migraine symptoms like nausea and sensitivity to light, is thought to be caused by both of these mechanisms.
Use this medicine according to how much and how long your doctor tells you to. Before you use something, check the label to see how to do it. Put the tip of the bottle into one nostril while you plug the other one. Aim the spray at the sides of your nostrils and avoid the cartilage that separates the two sides of your nose. Keep a calm breathing rate and a straight head while you spray. Do the same thing with the other nostrils.
When shouldn’t you use Zolmist?
Do not use Zolmist nasal spray 5mg if you:
- if you are allergic to zolmitriptan or any of the other ingredients in Zolmist
- if you are pregnant or nursing, if you have kidney or liver disease, or if your blood pressure is out of control.
- have ischaemic heart disease or a history of heart diseases, such as angina, stroke, or heart attack
- disease of the peripheral blood vessels
- have a rare and more serious type of migraine called hemiplegic or basilar migraine.
- are taking monoamine oxidase (MAO) inhibitors or have taken one in the past two weeks; are taking another migraine medicine, such as a 5-HT agonist like sumatriptan or an ergot derivative like methysergide; or have had a migraine in the past two weeks.
- are also taking beta-blockers like propranolol for high blood pressure, SSRIs or SNRIs for depression (like fluoxetine or venlafaxine), or cimetidine for acid reflux.
What other medicines can I take with Zolmist?
Several drugs interact with Zolmist nasal spray 5mg do not take other drugs while using Zolmist or only after talking to your doctor and following their instructions:
SSRIs (like fluoxetine) or SNRIs (like venlafaxine) for depression are dangerous when taken with Zolmist.
Zolmist is affected by these drugs:
MAO inhibitors treat depression, and beta-blockers like propranolol treat high blood pressure.
Zolmist can change the way drugs work, like cimetidine for acid reflux.
How do you take Zolmist?
Zolmist nasal spray 5mg can treat at any point during a migraine, but it works best if it is used as soon as possible after the first signs of headache and/or aura. You should spray one dose of Zolmist nasal spray 5mg into one nostril. Within 15 minutes, you should feel better, but you can use another dose if your headache comes back after two hours. If you have another migraine attack in the next 24 hours, you can take another dose, but you can’t take more than 10mg in 24 hours.